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2.
Psychosomatics ; 46(2): 123-30, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-15774950

RESUMO

The authors sought to identify the personality correlates of depressive symptoms in 120 spouses of people with lung cancer. Spouses completed questionnaires, including measures of personality (neuroticism, extraversion, and interpersonal self-efficacy), social support, and caregiving burden. Their level of depressive symptoms was measured with self-report (Center for Epidemiologic Studies Depression Scale) and interviewer (Hamilton Depression Rating Scale) ratings. Structural equation modeling showed that neuroticism was directly associated with greater depressive symptoms and indirectly associated with less social support and greater caregiving burden. Interpersonal self-efficacy was indirectly associated with the severity of depressive symptoms through both social support and caregiving burden. These findings have implications for identifying spouses of individuals with lung cancer who are vulnerable to depression and could inform the design of programs to reduce depressive symptoms in the context of cancer caregiving.


Assuntos
Cuidadores/psicologia , Efeitos Psicossociais da Doença , Depressão/diagnóstico , Neoplasias Pulmonares/psicologia , Personalidade , Apoio Social , Adulto , Idoso , Idoso de 80 Anos ou mais , Depressão/epidemiologia , Depressão/psicologia , Feminino , Humanos , Neoplasias Pulmonares/epidemiologia , Masculino , Pessoa de Meia-Idade , Variações Dependentes do Observador , Índice de Gravidade de Doença , Inquéritos e Questionários
3.
Psychosom Med ; 66(6): 950-3, 2004.
Artigo em Inglês | MEDLINE | ID: mdl-15564363

RESUMO

OBJECTIVE: We examined the influence of psychological state (depression, negative affect, perceived stress) and social support on pre- and post-vaccination response to influenza vaccine. METHODS: Venous blood was drawn from 37 nursing home residents before and following injection of the trivalent influenza vaccine (comprised of the New Caledonia (NC), Hong Kong (HK), and Panama (Pan) strains of flu). The Geriatric Depression Scale, Perceived Stress Scale, Positive and Negative Affect Schedule, and Multidimensional Scale of Perceived Social Support were completed following the initial blood draw. RESULTS: Social support and perceived stress were correlated with pre-vaccine antibody responses to two of the three vaccine components (HK and NC). Social support was negatively correlated with both pre- and post-vaccine titers to Pan. Depression, positive affect, and negative affect were not related to vaccine response. CONCLUSIONS: Perceived stress and social support influence the rate of decline of antibody titers to previous exposures to some strains of influenza occurring either naturally or via deliberate vaccination.


Assuntos
Formação de Anticorpos/imunologia , Avaliação Geriátrica , Vacinas contra Influenza/imunologia , Influenza Humana/prevenção & controle , Apoio Social , Estresse Psicológico/diagnóstico , Vacinação , Afeto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Anticorpos Antivirais/sangue , Anticorpos Antivirais/imunologia , Feminino , Humanos , Vírus da Influenza A/imunologia , Vacinas contra Influenza/uso terapêutico , Masculino , Vacinação em Massa/métodos , Casas de Saúde , Orthomyxoviridae/imunologia , Escalas de Graduação Psiquiátrica , Estresse Psicológico/psicologia , Vacinação/métodos
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